Cancer Progress

Progress of cancer genomics

For hundreds of years, cancer has remained a mystery, threatening the life expectancy and quality of all human beings. Early studies of cancer concluded that all cancers are influenced by genetic variation (germline and/or somatic), environmental agents, and/or health behaviors. Thus, a comprehensive description of the human genome is essential in order to understand the biology of cancer. Over...

Progress in pediatric cancer.

CLINICAL PROGRESS Metastatic Cancer

METASTATIC caneer to the heart assumes greater diagnostic and therapeutic importance as the incidence of cancer rises. The condition evidently was first described by Boneti in 1700.1 A report in the English literature appeared in 1822 of a case of testicular cancer with tumor filling the vena eava and extending to the edge of the Eustachian valve.2 Subsequent reports described metastases to all...

Progress in prostate cancer.

Sphingosylphosphorylcholine in cancer progress.

Sphingosylphosphorylcholine (SPC) is a naturally occurring bioactive sphingolipid in blood plasma, metabolizing from the hydrolysis of the membrane sphingolipid. It has been shown to exert multifunctional role in cell physiological regulation either as an intracellular second messenger or as an extracellular agent through G protein coupled receptors (GPCRs). Because of elevated levels of SPC in...